Kurouski Lab



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Reviews and book chapters:

9. Amyloid Diseases (2019); IntechOpen; Ed. Kurouski, D.; DOI: 10.5772/intechopen.73821; ISBN: 978-1-78985-382-7

8. Farber, C., Mahnke, M., Sanchez, L., Kurouski, D. (2019) Advanced Spectroscopic Techniques for Plant Disease Diagnostics. A Review. Trends Analyt. Chem., 118, 43-49.


7. Kurouski, D. (2018) Tip-Enhanced Raman Spectroscopy: An Emergent Technique for Probing Biology and Electrochemistry at the Nanoscale. Spectroscopy Magazine, 33, 38–46.


6. Kurouski, D. (2017) Advances of Vibrational Circular Dichroism (VCD) in Bioanalytical Chemistry. Anal. Chim. Acta., 990, 54-66.



5. Kurouski, D., Lee, H., Roschangar, F., Senanayake, C. (2017) Surface-Enhanced Raman Spectroscopy: From Concept to Practical Application. Spectroscopy Magazine, 32, 36-44.

4. Kurouski, D. (2017) Advances of tip-enhanced Raman spectroscopy (TERS) in electrochemistry, biochemistry, and surface science. Vibr. Spectrosc., 91, 3-15.

3. Kurouski, D. (2016) Supramolecular Organization of Amyloid Fibrils. In Amyloids, ed: Escamilla, A.M.F., Intech, ISBN 978-953-51-4716-9.

2. Jiang, N., Kurouski, D., Pozzi, E.A., Chiang, M., Hersam, M.C., Van Duyne, R.P. (2016) Tip-enhanced Raman spectroscopy: From concepts to practical applications. Phys. Lett., 659, 16-24.

1. Kurouski, D., Van Duyne, R.P., Lednev, I.K. (2015): Exploring the Structure and Formation Mechanism of Amyloid Fibrils by Raman Spectroscopy: A Review. Analyst, 140, 4967-4980.



Research articles:

50. Krimmer, M., Farber, C., Kurouski, D. (2019) Rapid and Non-Invasive Typing and Assessment of Nutrient Content of Maize Kernels Using A Hand-Held Raman Spectrometer. ACS Omega, accepted.


49. Sanchez, L., Pant, S., Irey, M., Mandadi, K., Kurouski, D. (2019) Detection and Identification of Canker and Blight on Orange Trees Using a Hand-Held Raman Spectrometer. J. Raman Spectrosc., accepted.


48. Rizevsky, S., Kurouski, D. (2019) Nanoscale Structural Organization of Insulin Fibril Polymorphs Revealed By Atomic Force Microscope Infrared Spectroscopy (AFM-IR). ChemBioChem, accepted.


47. Farber, C., Shires, M., Ong, K., Byrne, D., Kurouski, D. (2019) Raman spectroscopy as an early detection tool for rose rosette infection. Planta, accepted.


46. Esparza, I., Wang, R., Kurouski, D. (2019) Surface-Enhanced Raman Analysis of Underlaying Colorants On Re-Dyed Hair. Anal. Chem., 91, 7313-7318.


45. Sanchez, L., Pant, S., Xing, Z., Mandadi, K., Kurouski, D. (2019) Rapid and Non-invasive Diagnostics of Huanglongbing and Nutrient Deficits on Citrus Trees with a Hand-Held Raman Spectrometer. Anal. Bioanal. Chem., 411, 3125–3133.



44. Farber, C., Li, J., Hager, E., Chemelewski, R., Mullet, J., Rogachev, A., Kurouski, D. (2019) Complementarity of Raman and Infrared Spectroscopy for Structural Characterization of Plant Epicuticular Waxes. ACS Omega, 4, 3700-3707.


43. Farber, C., Wang, R., Chemelewski, R., Mullet, J., Kurouski, D. (2019) Nanoscale Structural Organization of Plant Epicuticular Wax Probed by Atomic Force Microscope Infrared Spectroscopy Anal. Chem., 912472–2479.


42. Sanchez, L., Farber, C., Lei, J., Zhu-Salzman, K., Kurouski, D. (2019) Non-Invasive and Non-Destructive Detection of Cowpea Bruchid Within Cowpea Seeds with a Hand-Held Raman Spectrometer Anal. Chem., 91, 1733–1737.


41. Wang, R., Kurouski, D. (2018) Elucidation of Tip-Broadening Effect in Tip-Enhanced Raman Spectroscopy (TERS): A Cause of Artifacts or Potential for 3D TERS J. Phys. Chem. C122, 24334–24340.


40. Egging, V., Nguyen, V., Kurouski, D. (2018) Detection and Identification of Fungal Infections in Intact Wheat and Sorghum Grain Using a Hand-Held Raman Spectrometer Anal. Chem.90, 8616-8621.


39. Hager, E., Farber, C., Kurouski, D. (2018) Forensic Identification of Urine on Cotton and Polyester Fabric with a Hand-held Raman Spectrometer Forensic Chem., 9, 44-49.


38. Farber, C. and Kurouski, D. (2018) Detection and Identification of Plant Pathogens on Maize Kernels with a Handheld Raman Spectrometer Anal. Chem., 90, 3009-3012.


Prior to Texas A&M

  1. Qu, B., Mangunuru, H.P.R., Tcyrulnikov, S., Rivalti, D., Zatolochnaya, O., Kurouski, D., Radomkit, S., Biswas, S., Karyakarte, S., Fandrick, K.R., Sieber, J.D., Rodriguez, S., Desrosiers, N.-J., Haddad, N., Grinberg, N., Yee, N.K., Song, J.J., Kozlowski, M.C., Senanayake, C.H. (2018) Enantioselective Synthesis of α-(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights. J. Org. Chem. 20, 1333-1337.


  1. Sieber, J.D., Rodriguez, S., Frutos, R., Buono, F., Zhang, Y., Li, N., Qu, B., Premasiri, A., Li, Z., Han, Z., Xu, Y., Bryne, D., Haddad, N., Lorenz, J., Grinberg, N., Kurouski, D., Lee, H., Narayanan, B., Nummy, L., Mulder, J., Brown, J., Granger, A., Krawiec, M., Williams, Z., Pennino, S., Song, J., Hossain, A., Yee, N., Brusacca, C., Roschangar, F., Xin, Y., Mao, Z., Zhang, X., Hong, Y., Senanayake, C.H. (2018) Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative in High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation. J. Org. Chem., 83, 1448-1461.


  1. Kurouski, D., Large, N., Chiang, N., Henry, A. -I., Seideman, T., Schatz, G.C., Van Duyne, R.P. (2017) Unraveling Near- and Far-Field Relationship of 2D SERS Substrates Using Wavelength-Scanned Surface-Enhanced Raman Excitation Spectroscopy (WS-SERES). J. Phys. Chem. C, 121, 14737–14744.


  1. Desrosiers, J.N., Wen, J., Tcyrulnikov, S., Biswas, S., Qu, B., Hie, L., Kurouski, D., Wu, L., Grinberg, N., Haddad, N., Busacca, C.A., Yee, N.K., Song, J.J., Garg, N.K., Zhang, X., Kozlowski, M.C., Senanayake, C.H. (2017) Enantioselective Nickel-Catalyzed Mizoroki-Heck Cyclizations To Generate Quaternary Stereocenters. Org. Lett., 19, 3338-3341.


  1. Li, S.-G., Han, Z.S., Viereck, P., Kurouski, D., Senanayake, C.H., Tsantrizos, Y.S. (2017) Metal-Free Cycloetherification by in Situ Generated P-Stereogenic α-Diazanium Intermediates: A Convergent Synthesis of Enantiomerically Pure Dihydrobenzooxaphospholes. Org. Lett., 19, 894-897.


  1. Qu, B., Mangunuru, H.P.R., Wei, H., Fandrick, K.R., Desrosiers, N.-J., Sieber, J.D., Kurouski, D., Haddad, N., Samankumara, L.P., Lee, H., Savoie, J., Ma, S., Grinberg, N., Sarvestani, M., Yee, N.K., Song, J.J., Senanayake, C.H. (2016) Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts. Org. Lett., 18, 4920-4923.


  1. Haddad, N., Mangunuru, H.P.R., Fandrick, K.R., Qu, B., Sieber, J.D., Rodriguez, S., Desrosiers, N.-J., Patel, N. D., Lee, H., Kurouski, D., Grinberg, N., Yee, N.K., Song, J.J., Senanayake, C.H. (2016) Reengineered BI-DIME Ligand Core Based on Computer Modeling to Increase Selectivity in Asymmetric Suzuki–Miyaura Coupling for the Challenging Axially Chiral HIV Integrase Inhibitor. Synth. Catal., 358, 3522-3527.


  1. Sieber, J.D., Angeles-Dunham, V.V.,  Chennamadhavuni, D.,  Fandrick, D.R.,  Haddad, N.,  Grinberg, N.,  Kurouski, D.,  Lee, H.,  Song, J.J.,  Yee, N.K.,  Mattson, A.E.,  Senanayake, C.H. (2016) Rhodium-Catalyzed Asymmetric Allenylation of Sulfonylimines and Application to the Stereospecific Allylic Allenylation. Synth. Catal., 358, 3062-3068.


  1. Deckert-Gaudig, T., Kurouski, D., Hedegaard, M., Singh, P., Lednev, I.K., Deckert, V. (2016): Spatially resolved spectroscopic differentiation of hydrophilic and hydrophobic domains on individual insulin amyloid fibrils. Sci. Rep., 6, 33575.


  1. Breydo, L., Kurouski, D., Rasool, S., Milton, S., Wu, J.W., Uversky, V.N., Lednev, I.K., Glabe, C.G. (2016) Structural differences between amyloid beta oligomers. Biophys. Res. Commun., 477, 700-705.


  1. Henry, A.-I., Sharma, B., Cardinal, M.F., Kurouski, D., Van Duyne, R.P. (2016) Surface-enhanced Raman spectroscopy biosensing: In vivo diagnostics and multimodal imaging. Anal. Chem., 88, 6638–6647.


  1. Kurouski, D., Chiang, N. Large, N. Greeneltch, K. T. Carron, T. Seideman, G. C. Schatz, Van Duyne, R.P. (2016): Unraveling Near-Field and Far-Field Relationships for 3D SERS Substrates – A Combined Experimental and Theoretical Analysis. Analyst, 141, 1779 – 1788.


  1. Kurouski, D., Mattei, M., Van Duyne, R.P. (2015): Probing Redox Reactions at the Nanoscale with Electrochemical Tip-Enhanced Raman Spectroscopy. Nano Lett., 15, 7956-7962.


  1. Shanmugasundaram, M., Kurouski, D., Wan, W., Stubbs, G., Dukor, R.K., Nafie, L.A., Lednev, I.K. (2015): Rapid filament supramolecular chirality reversal of HET-s (218-289) prion fibrils driven by pH elevation. J. Phys. Chem. B, 119, 8521–8525.


  1. Kurouski, D., Van Duyne, R.P. (2015): In situ detection and identification of hair dyes using surface-enhanced Raman spectroscopy (SERS). Anal. Chem., 87, 2901-2906 (highlighted by Science, ACS News, Phys.Org, The Analytical Scientist and USA Today).


  1. Rosario-Alomar, M.F., Quiñones-Ruiz, T., Kurouski, D., Sereda, V., Ferreira, E.B., Jesús-Kim, L.D., Hernández-Rivera, S., Zagorevski, D.V., López-Garriga, J., Lednev, I.K. (2015): Hydrogen sulfide inhibits amyloid formation. J. Phys. Chem. B, 119, 1265-1274.


  1. Kurouski, D., Handen, J.D., Dukor, R.K., Nafie, L.A., Lednev, I.K. (2015): Supramolecular chirality in peptide microcrystals. Chem.Commun., 51, 89-92.


  1. Kurouski, D., Zaleski, S., Casadio, F., Van Duyne, R.P., Shah, N.C. (2014): Tip-enhanced Raman spectroscopy (TERS) for in situ identification of indigo and iron gall ink on paper. Am. Chem. Soc., 136, 8677-8684 (made C&EN news article).


  1. Kurouski, D., Lu, X., Popova, L., Wan, W., Shanmugasundaram, M., Stubbs, G., Dukor, R.K., Lednev, I.K., Nafie, L.A. (2014): Is supramolecular filament chirality the underlying cause of major morphology differences in amyloid fibrils? J. Am. Chem. Soc., 136, 2302-2312.


  1. Kurouski, D., Deckert-Gaudig, T., Deckert, V., Lednev, I.K. (2014): Surface characterization of insulin protofilaments and fibril polymorphs using tip-enhanced Raman spectroscopy (TERS). Biophys.J., 106, 263-271 (made a journal cover).


  1. Kurouski, D., Sorci, M., Postiglione, T., Belfort, G., Lednev, I.K. (2014): Detection and structural characterization of insulin prefibrilar oligomers using surface enhanced Raman spectroscopy. Biotechnol.Prog., 30, 488-495.


  1. Kurouski, D., Luo, H., Sereda, V., Robb, F.T., Lednev, I.K. (2013): Deconstruction of stable cross-beta fibrillar structures into toxic and nontoxic products using a mutated archaeal chaperonin. ACS Chem. Biol., 8, 2095-2101.


  1. Bhat, V., Olenick, M.B., Schuchardt, B.J., Mikles, D.C., Deegan, B.J., McDonald, C.B., Seldeen, K.L., Kurouski, D., Faridi, M.H., Shareef, M.M., Gupta, V., Lednev, I.K., Farooq, A. (2013): Heat-induced fibrillation of BclXL apoptotic repressor. Biophys. Chem., 179, 12-25.


  1. Kurouski, D., Kar, K., Wetzel, R., Dukor, R.K., Lednev, I.K., Nafie, L.A. (2013): Levels of supramolecular chirality of polyglutamine aggregates revealed by vibrational circular dichroism. FEBS Lett., 587, 1638-1643.


  1. McDonald, C.B., Bhat, V., Kurouski, D., Mikles, D.C., Deegan, B.J., Seldeen, K.L., Lednev, I.K., Farooq, A. (2013): Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor. Biophys.Chem., 175-176, 54-62.


  1. Kurouski, D., Postiglione, T., Deckert-Gaudig, T., Deckert, V., Lednev, I.K. (2013): Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens. Analyst, 138, 1665-1673 (made a journal cover).


  1. Srinivasan, S., Patke, S., Wang ,Y., Ye, Z., Litt, J., Srivastava, S.K., Lopez, M.M., Kurouski, D., Lednev, I.K., Kane, R.S., Colón, W. (2013): Pathogenic serum amyloid A1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2. J. Biol. Chem., 288, 2744-2755.


  1. Bhat, V., Kurouski, D., Olenick, M.B., McDonald, C.B., Mikles, D.C., Deegan, B.J., Seldeen, K.L., Lednev, I.K., Farooq, A. (2012): Acidic pH promotes oligomerization and membrane insertion of the BclXL apoptotic repressor. Biochem. Biophys., 528, 32-44.


  1. Kurouski, D., Dukor, R.K., Lu, X., Nafie, L.A., Lednev, I.K. (2012): Normal and reversed supramolecular chirality of insulin fibrils probed by vibrational circular dichroism at the protofilament level of fibril structure. Biophys.J., 103, 522-531.


  1. Kurouski, D., Deckert-Gaudig, T., Deckert, V., Lednev, I.K. (2012): Structure and composition of insulin fibril surfaces probed by TERS. J. Am. Chem. Soc., 134, 13323-13329.


  1. Kurouski, D., Washington, J., Ozbil, M., Prabhakar, R., Shekhtman, A., Lednev, I.K. (2012): Disulfide bridges remain intact while native insulin converts into amyloid fibrils. PLoS One, 7, e36989.


  1. Kurouski, D., Luo, H., Sereda, V., Robb, F.T., Lednev, I.K. (2012): Rapid degradation kinetics of amyloid fibrils under mild conditions by an archaeal chaperonin. Biochem. Biophys. Res. Commun., 422, 97-102.


  1. Kurouski, D., Dukor, R.K., Lu, X., Nafie, L.A., Lednev, I.K. (2012): Spontaneous inter-conversion of insulin fibril chirality. Chem. Commun., 48, 2837-2839 (made a journal cover).


  1. Heldt, C.L., Kurouski, D, Sorci, M., Grafeld, E., Lednev, I.K., Belfort, G. (2011): Isolating toxic insulin amyloid reactive species that lack β-sheets and have wide pH stability. Biophys. J., 100, 2792-2800.


  1. Kurouski, D., Lednev, I.K. (2011): The impact of protein disulfide bonds on the amyloid fibril morphology. Int. J. Biomed. Nanosci. Nanotech., 2, 167-176.


  1. Kurouski, D., Lombardi, R.A., Dukor, R.K., Lednev, I.K., Nafie, L.A. (2010) Direct observation and pH control of reversed supramolecular chirality in insulin fibrils by vibrational circular dichroism. Chem.Commun. 46, 7154-7156.


  1. Kurouski, D., Lauro, W., Lednev, I.K. (2010): Amyloid fibrils are “alive”: spontaneous refolding from one polymorph to another. Chem. Commun., 46, 4249-4251 (made a journal cover).


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